KMID : 0377519840090010015
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Chung-Ang Journal of Medicine 1984 Volume.9 No. 1 p.15 ~ p.22
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A Study on Distribution of Rat Spermatogenie Cells - An Effect of Aging
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Kim Rhan-Hee
Kim Ho-Dirk Lee Won-Bok Rah Bong-Jin
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Abstract
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For the study of aging effect on spermatogenesis, forty-three albino rats of Sprague-Dawley strain were used as experimental animals. After fixation of testes with Bouin¡¯s solution, 5 § thick sections were stained with periodic acid-Schiff hematoxylin and examined by light microscope.The results obtained were as follows: 1. The histological findings of the non-atrophied testes of eighty-week old rats and the testes of fifteen-week old control were quite normal. The unilaterally or bilaterally atrophied testes showed atrophied seminiferous tubules, thickened basal lamina, and increased fibrosis in the interstitium. There was degenerative change in the epithelium of seminiferous tubules and spermatogenesis was not noticed. 2. The numbers of primary spermatocyte of preleptotene stage and pachytene stage and spermatids in the tubules of non-atrophied testes of eighty-week old rats did not show significant differences in comparison with those of fifteen-week old rats. The above findings show that there might not be any changes in spermatogenesis in the aged testes which are not atrophied.
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